Fergana region is situated in Fergana Valley. It is a rich agricultural region, producing cotton, grain, rice, fruits and vegetables. There is also a significant industrial base in the region, with major industries being agricultural production and processing, agricultural machinery, oil and oil refinery, chemicals and fertilizers.

The Fergana Region has 4 administrative cities and 15 rural districts. The capital is the city of Fergana; other major cities include Besharik, Khamza, Kokand, Kuva, Kuvasay, Margilan and Rishtan. There are two Uzbek exclaves in the territory of Fergana region. They are the district of Sokh and Shahimardan. Fergana is one of the most industrially developedregions in Uzbekistan with over 170 industrial enterprises. There are airports in Kokand and Fergana city.

The main agriculturalsectors are dominatedby cotton followed by silkworm breeding and gardening. The main products of the region are gain, potatoes, vegetables, fruits, meat, milk, and eggs. The most developed branches of the economy are textile, silk processing, chemicals, and oil processing. With the development of the oil and gas sector, the region developed a substantial expertise in engineering, construction, and manufacture of building materials.

One of the biggest challenges for local manufacturers of fruits and vegetables are lackof modern storage, processing and packaging facilities and equipment. Processing of agricultural products is a sector that the Government has targeted for development.